At HTL Biosolutions, Inc., we offer both consulting and contract research services on protein size variant characterizations.  In a close alliance with Protein Alliance Laboratory, Inc., we offer a array of comprehensive contract research service in protein characterizations. 

Protein size variants include native state, aggregates, oligomers and clips are important parameters that need to be fully characterized during regulatory filing.  The size variants can be characterized by using the following analytical methods:

Gel electrophoresis/capillary electrophoresis

SEC-HPLC to quantify protein aggregates and clips.

Light scattering techniques such as on-line SEC light scattering and Dynamic Light Scattering (DLS)